Current Oncology, Free Full-Text
Por um escritor misterioso
Last updated 26 junho 2024
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Background: Information on immune responses in cancer patients following mRNA COVID-19 vaccines is still insufficient, but generally, patients had impaired serological responses, especially those with hematological malignancies. We evaluated serological response to COVID-19 mRNA vaccine in cancer patients receiving chemotherapy compared with healthy controls. Methods: In total, 195 cancer patients and 400 randomly selected controls who had been administered a Pfizer-BioNTech or Moderna COVID-19 vaccines in two doses were compared. The threshold of positivity was 4.33 BAU/mL. Patients were receiving anticancer treatment after the first and second dose of the vaccines. Results: a TOTAL OF 169 patients (87%) had solid tumors and 26 hemolymphopoietic diseases. Seropositivity rate was lower in patients than controls (91% vs. 96%), with an age/gender-adjusted rate ratio (RR) of 0.95 (95% CL = 0.89–1.02). Positivity was found in 97% of solid cancers and in 50% of hemolymphopoietic tumors. Both advanced and adjuvant therapy seemed to slightly reduce seropositivity rates in patients when compared to controls (RR = 0.97, 95% CL = 0.89–1.06; RR = 0.94, 95% CL = 0.87–1.01). Conclusions: the response to vaccination is similar in patients affected by solid tumors to controls. On the contrary, hemolymphopietic patients show a much lower response than controls.
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Current Oncology An Open Access Journal from MDPI
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Free Oncology CE and CME for Healthcare Professionals
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Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer
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Current Oncology An Open Access Journal from MDPI
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Frontiers Cell-Free DNA: Hope and Potential Application in Cancer
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Finding Mr. Destiny Arabic Sub - Colaboratory
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Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer
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Current Oncology
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Dr. Susan Love's Breast Book: Love MD, Susan M., Love, Elizabeth: 9780306833250: : Books
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touchONCOLOGY - Online Education for Oncology Professionals
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Current Issue Table of Contents: Advances in Radiation Oncology
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