Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
Por um escritor misterioso
Last updated 29 junho 2024
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://pubs.acs.org/cms/10.1021/acs.jmedchem.7b01854/asset/images/medium/jm-2017-01854x_0009.gif)
Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://www.ahajournals.org/cms/asset/a73942f6-cde4-4555-a694-2256a71e1a32/35ff1.jpg)
A Potential Role of the CXC Chemokine GROα in Atherosclerosis and Plaque Destabilization
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://www.biorxiv.org/content/biorxiv/early/2022/05/31/2022.05.30.494024/F2.large.jpg)
Development of fluorescent peptide G Protein Coupled Receptor activation biosensors for NanoBRET characterisation of intracellular allosteric modulators
Highly enantioselective borane reduction of ketones catalyzed by chiral oxazaborolidines. Mechanism and synthetic implications
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://patentimages.storage.googleapis.com/29/7c/0e/76e009fcdb2d57/imgf000026_0001.png)
WO2014033122A1 - Inhibitors of cd40-traf6 interaction - Google Patents
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://europepmc.org/articles/PMC6556150/bin/nihms-1029202-f0001.jpg)
Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts. - Abstract - Europe PMC
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://ars.els-cdn.com/content/image/1-s2.0-S0223523420303573-fx1.jpg)
Discovery, structure-activity relationship study and biological evaluation of 2-thioureidothiophene-3-carboxylates as a novel class of C-X-C chemokine receptor 2 (CXCR2) antagonists - ScienceDirect
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://www.tsbiochem.com/content/xtheme/guanwang/images/qr_weixin.png)
AS 6 陶术生物
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://www.biorxiv.org/content/biorxiv/early/2022/05/31/2022.05.30.494024/F6.large.jpg)
Development of fluorescent peptide G Protein Coupled Receptor activation biosensors for NanoBRET characterisation of intracellular allosteric modulators
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://c5.rgstatic.net/m/437738464651637/images/template/default/profile/profile_default_l.jpg)
Sophie GONG, Sr. scientist, GlaxoSmithKline, London, GSK, R&D China
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://pubs.acs.org/cms/10.1021/acs.jmedchem.7b01854/asset/images/medium/jm-2017-01854x_0001.gif)
Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://pubs.acs.org/cms/10.1021/acs.jmedchem.7b01854/asset/images/medium/jm-2017-01854x_0014.gif)
Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://ars.els-cdn.com/content/image/1-s2.0-S0223523423009340-gr10.jpg)
Advances in targeting Phosphodiesterase 1: From mechanisms to potential therapeutics - ScienceDirect
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://ars.els-cdn.com/content/image/1-s2.0-S0045206821004818-ga1.jpg)
Design, synthesis and biological evaluation of novel pyrazolopyrimidone derivatives as potent PDE1 inhibitors - ScienceDirect
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