Nutrients, Free Full-Text
Por um escritor misterioso
Last updated 01 julho 2024
![Nutrients, Free Full-Text](https://www.mdpi.com/nutrients/nutrients-13-01642/article_deploy/html/images/nutrients-13-01642-g001.png)
The mesencephalic trigeminal nucleus (Mes5) processes oral sensory–motor information, but its role in the control of energy balance remains unexplored. Here, using fluorescent in situ hybridization, we show that the Mes5 expresses the melanocortin-4 receptor. Consistent with MC4R activation in other areas of the brain, we found that Mes5 microinjection of the MC4R agonist melanotan-II (MTII) suppresses food intake and body weight in the mouse. Furthermore, NTS POMC-projecting neurons to the Mes5 can be chemogenetically activated to drive a suppression in food intake. Taken together, these findings highlight the Mes5 as a novel target of melanocortinergic control of food intake and body weight regulation, although elucidating the endogenous role of this circuit requires future study. While we observed the sufficiency of Mes5 MC4Rs for food intake and body weight suppression, these receptors do not appear to be necessary for food intake or body weight control. Collectively, the data presented here support the functional relevance of the NTS POMC to Mes5 projection pathway as a novel circuit that can be targeted to modulate food intake and body weight.
![Nutrients, Free Full-Text](https://i.pinimg.com/736x/3c/e9/61/3ce961f4374fba45a2ca26ffd8f56615.jpg)
Nutrients, Free Full-Text, One Giant Leap from Mouse to Man: The Microbiota–Gut–Brain Axis in Mood Disor… in 2023
![Nutrients, Free Full-Text](https://pub.mdpi-res.com/nutrients/nutrients-15-02141/article_deploy/html/images/nutrients-15-02141-g001-550.jpg?1682756955)
Ssb Personal Interview Video Download - Colaboratory
![Nutrients, Free Full-Text](https://pub.mdpi-res.com/announcement/7192.jpg?1702894284)
Nutrients An Open Access Journal from MDPI
![Nutrients, Free Full-Text](https://www.mdpi.com/nutrients/nutrients-05-00829/article_deploy/html/images/nutrients-05-00829-g002-1024.png)
Nutrients, Free Full-Text
![Nutrients, Free Full-Text](https://www.hartgoods.com/wp-content/uploads/Food-Synergy-Cover-Sample-1000w.jpg)
Eating like a God - Whole Food & Nutrient Synergy - Sample
![Nutrients, Free Full-Text](https://www.mdpi.com/nutrients/nutrients-05-04305/article_deploy/html/images/nutrients-05-04305-g002-1024.png)
Nutrients, Free Full-Text
![Nutrients, Free Full-Text](https://www.mdpi.com/nutrients/nutrients-04-01622/article_deploy/html/images/nutrients-04-01622-g005-1024.png)
Nutrients, Free Full-Text
![Nutrients, Free Full-Text](https://www.mdpi.com/nutrients/nutrients-08-00017/article_deploy/html/images/nutrients-08-00017-g001-1024.png)
Nutrients, Free Full-Text
![Nutrients, Free Full-Text](https://chunginstitute.com/wp-content/uploads/2023/01/nutrients.png)
Won Sook Chung Foundation sponsored vitamin D study published in Nutrients! – CHUNG INSTITUTE OF INTEGRATIVE MEDICINE
Recomendado para você
-
The Phantom Workshop - SCP Foundation01 julho 2024
-
Jennifer Swann - SCP Art: SCP-040 Evolution's Child01 julho 2024
-
SCP-5673-1, Wiki01 julho 2024
-
SCP-096 Slaughter Fest!!! [SCP: Secret Laboratory]01 julho 2024
-
GTFO my Department Bich : r/SS1301 julho 2024
-
DS4 weird USB behavior · Issue #969 · nefarius/ScpToolkit · GitHub01 julho 2024
-
SCP-682 on X: @peta / X01 julho 2024
-
Sulfachloropyridazine (SCP) effects on anaerobic microorganisms01 julho 2024
-
It's not scramble you idiots : r/SCPSecretLab01 julho 2024
-
SCP : Observer No Commentary #101 julho 2024
você pode gostar
-
Furanshis - Kun - This scene,Just KISS already! 💓01 julho 2024
-
BIG BRUNCH- PINK PANTHER EDITION, Big Leagues Sports & Games Lounge, Accra, January 7 202401 julho 2024
-
Unravel Two, Jogo Nintendo Switch01 julho 2024
-
Play New Year's Dino Run Online - Free Browser Games01 julho 2024
-
O ROBLOX ANTIGO !01 julho 2024
-
Loki Episódio 2 da 2ª temporada tem cena pós-créditos?01 julho 2024
-
Desenho de Menina com vestido moderno pintado e colorido por01 julho 2024
-
alem da fé jason ferrer01 julho 2024
-
Are you guys ready for my dark sonic mod? it WILL be out, i promise😥 : r/FridayNightFunkin01 julho 2024
-
How To Block in My Hero Ultra Rumble01 julho 2024