Pathogens, Free Full-Text
Por um escritor misterioso
Last updated 31 maio 2024
Acute chagasic encephalitis is a clinically severe central nervous system (CNS) manifestation. However, the knowledge of the nervous form of Chagas disease is incomplete. The role of the muscarinic acetylcholine receptor (mAChR) on mice behavior and brain lesions induced by Trypanosoma cruzi (Colombian strain) was herein investigated in mice treated with the mAChR agonist and antagonist (carbachol and atropine), respectively. Immunosuppressed or non-immunosuppressed mice were intracerebroventricularly (icv) or intraperitoneally (ip) infected. All groups were evaluated 15 d.p.i. (days post infection). Intraperitoneally infected animals had subpatent parasitemia. Patent parasitemia occurred only in icv infected mice. The blockade of mAChR increased the parasitemia, parasitism and lesions compared to its activation. Infected not treated (INT ip) mice did not present meningitis and encephalitis, regardless of immunosuppression. INT icv brains presented higher cellularity, discrete signs of cellular degeneration, frequent presence of parasites and focal meningitis. The immunosuppressed atropine + icv mice presented increased intracellular parasitism associated with degenerative parenchymal changes, while carbachol + icv mice presented discrete meningitis, preservation of the cortex and absence of relevant parasitism. Cholinergic receptor blockage increased impairment of coordination vs. receptor activation. Muscarinic cholinergic pathway seems to be involved in immune mediated cell invasion events while its blockade favored infection evolution, brain lesions, and behavioral alterations.
What is a pathogen? - 4-H Animal Science
Pathogens, Free Full-Text
A culture-free biphasic approach for sensitive and rapid detection of pathogens in dried whole-blood matrix
Www Raymond Cc Blog Did 2594 - Colaboratory
Pathogens, Free Full-Text
Ecological and socioeconomic factors associated with the human burden of environmentally mediated pathogens: a global analysis - The Lancet Planetary Health
Deadly Bangladesh Strain Of Nipah Virus Claims 90% Of Infected Lives: Urgent Actions Required, Says Ex-ICMR Scientist - Inventiva
Pathogen Definition - Discover the meaning of pathogens, its impact and related articles
Pathogenic bacteria - Wikipedia
Programing of an Intravascular Immune Firewall by the Gut Microbiota Protects against Pathogen Dissemination during Infection - ScienceDirect
Recomendado para você
-
Xadrez Potiguar31 maio 2024
-
Espaço Xadrez Magazine by Saulo Loureiro - Issuu31 maio 2024
-
därför är d-vitamin viktigt för barn31 maio 2024
-
Kewpie young minds show excellence31 maio 2024
-
2023 African Individual Championships - The Chess Drum31 maio 2024
-
Atleta da FRXE se destaca nos Jogos Escolares Brasileiro JEBs 2023, Esportes31 maio 2024
-
AABB Campo Grande (MS)31 maio 2024
-
2023 ChessKid YSCC First Round Results and Upcoming Semifinals31 maio 2024
-
Enxadristas de MS se destacam no Pan-Americano de Xadrez Escolar e31 maio 2024
-
Crianças do DF vão representar Brasil em campeonato mundial de31 maio 2024
você pode gostar
-
AO ASHI SEASON 2 RELEASE DATE SITUATION!31 maio 2024
-
Peça De Xadrez Torre Decoração Em Cerâmica Azul Fosco31 maio 2024
-
NaruHina Brasil - Bom dia! ⚡ O twitter oficial do anime Boruto postou essa arte fofa dos nossos favoritos para anunciar o ínicio do período de hiato do anime por conta da31 maio 2024
-
Sonic Mania Plus ✪ Neo Metal Sonic Boss Mod31 maio 2024
-
Chloe Grace Moretz Recalls Struggling with Paparazzi at 12 Years Old31 maio 2024
-
Wither Storm 231 maio 2024
-
Jogo Garfo Faca Inox 24 Peças Restaurante Buffet Talheres31 maio 2024
-
Ace Attorney Online31 maio 2024
-
Uno No Mercy Edition31 maio 2024
-
SHOGI (DOUBUTSU) - XADREZ JAPONÊS - JOGO DE TABULEIRO Archives - Portal Neuro Ensino31 maio 2024