Site-specific phosphorylations of the Arf activator GBF1 differentially regulate GBF1 function in Golgi homeostasis and secretion versus cytokinesis

Src activates retrograde membrane traffic through phosphorylation of GBF1

Oligomerization of the Sec7 domain Arf guanine nucleotide exchange factor GBF1 is dispensable for Golgi localization and function but regulates degradation

The inhibition of cytoplasmic dynein motor activity reduces GBF1

GBF1 sequence determines BFA resistance of cells and virus. A.

LG186 reversibly inhibits GBF1 function in human (HeLa) cells. One-hour

GBF1 preferentially binds to Rab1b-GTP. (A) GST pulldown assays

Frontiers The Arf-GEF GBF1 undergoes multi-domain structural shifts to activate Arf at the Golgi

LG186, a potent and selective inhibitor of GBF1. A) HeLa cells

Phosphorylation of GBF1 by AMPK in mitosis. ( A ) HEK293 cells were

Src activates retrograde membrane traffic through phosphorylation of GBF1

Arf1 deficient mutants induce the condensation of the mitochondrial

Site-specific phosphorylations of the Arf activator GBF1 differentially regulate GBF1 function in Golgi homeostasis and secretion versus cytokinesis